Article

Reprogrammed neutrophils with impaired transit mechanics drive multi-organ capillary stalling after stroke

2026-02-11

Abstract excerpt

Beyond the focal brain lesion, stroke causes systemic complications including cardiac failure, pneumonia, renal injury, and sustained immune dysfunction. The source of this multiorgan vulnerability remains unresolved. By imaging over 16,000 vessels of healthy, inflamed and ischemic brains, we identify a circulating neutrophil subpopulation reprogrammed by stroke into a pathological stalling phenotype, occluding ca...

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Literature Corpus work: ed2144e2-37e0-58b8-a234-19621c3cb8a7
DOI: 10.64898/2026.02.10.705064

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