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Article

Polymorphisms in DNA repair genes increase the risk for type 2 diabetes mellitus and hypertension.

Biomolecular concepts - 9 Jun 2018

Das Sambuddha, Purkayastha Sukanya, Roy Hirakjyoti, Sinha Anima, Choudhury Yashmin

Abstract excerpt

We investigated the effect of polymorphisms in four DNA repair genes, viz. RAD18 Arg302Gln (G>A) (rs373572), XPD Asp312Asn (G>A) (rs1799793), APE1 Asp148Glu (T>G) (rs3136820), and OGG1 Ser326Cys (C>G) (rs1052133) on the risk for type 2 diabetes mellitus (T2DM) and hypertension (HT) in association with smoking, tobacco chewing, and alcohol consumption in a population from Northeast India. The study subjects were...

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Source

Identifiers

PMID: 29886452
DOI: 10.1515/bmc-2018-0008

Genes

RAD18
OGG1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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