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Article

DNA repair gene polymorphisms at XRCC1, XRCC3, XPD, and OGG1 loci in Maharashtrian population of central India.

Chemosphere - 1 Feb 2011

Pramanik Sreemanta, Devi Saravana, Chowdhary Sanghamitra, Surendran Subin T, Krishnamurthi Kannan, Chakrabarti Tapan

Abstract excerpt

Reduction in DNA repair capacity is associated with increased rates of birth defects, cancer, and accelerated ageing. Genetic polymorphisms in DNA repair genes might influence the repair activities of the enzymes predisposing individuals to cancer risk. Owing to the presence of these genetic variants, inter-individual and ethnic differences in DNA repair capacity have been observed in various populations. India...

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Identifiers

PMID: 21183201
DOI: 10.1016/j.chemosphere.2010.10.100

Genes

OGG1
XRCC1
XRCC3

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