Article
Association of Superoxide dismutases (SOD1 and SOD2) and Glutathione peroxidase 1 (GPx1) gene polymorphisms with type 2 diabetes mellitus.
Free radical research - 1 Jan 2015
Vats P, Sagar N, Singh T P, Banerjee M
Abstract excerpt
Type 2 diabetes mellitus (T2DM) is a metabolic disorder resulting from oxidative stress (OS), the root cause of insulin resistance, β-cell dysfunction, and impaired glucose tolerance. Antioxidant enzymes play key roles in cellular defense and can be used as important biomarkers for T2DM. The present study was undertaken to evaluate three genetic polymorphisms viz. SOD1 + 35A/C, SOD2 + 47C/T, and GPx + 599C/T in...
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