Article
Polymorphisms in oxidative stress pathway genes and risk of diabetic nephropathy in South Indian type 2 diabetic patients.
Nephrology (Carlton, Vic.) - 1 Oct 2014
Narne Parimala, Ponnaluri Kamakshi Chaithri, Siraj Mohammed, Ishaq Mohammed
Abstract excerpt
AIM: Diabetic nephropathy (DN), a common microvascular complication of type 2 diabetes mellitus (T2DM) is polygenic, with a vast array of genes contributing to disease susceptibility. Accordingly, we explored the association between DN and six polymorphisms in oxidative stress related genes, namely eNOS, p22phox subunit of NAD(P)H oxidase, PARP-1 and XRCC1 in South Indian T2DM subjects. METHODS: The study...
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