Article
Polymorphisms in DNA repair and multidrug resistance genes among Sindhis of Central India.
Environmental toxicology and pharmacology - 1 Sept 2015
Pramanik Sreemanta, Surendran Subin T, Arumugam Sathishkumar, Devi Saravana, Krishnamurthi Kannan, Chakrabarti Tapan
Abstract excerpt
Polymorphisms in DNA repair and multidrug resistance genes might contribute to interindividual and interethnic differences in DNA repair capacity and drug disposition respectively. In the present study, we determined the allele and genotype frequencies of four single nucleotide polymorphisms (SNPs) located in the DNA repair genes, XRCC1, XRCC3, XPD, OGG1, namely XRCC1 Arg399Gln, XRCC3 Thr241Met, XPD Lys751Gln,...
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