Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Have compensatory mutations facilitated the current epidemic of multidrug-resistant tuberculosis?

Emerging microbes & infections - 6 Jun 2018

Liu Qingyun, Zuo Tianyu, Xu Peng, Jiang Qi, Wu Jie, Gan Mingyu, Yang Chongguang, Prakash Ravi, Zhu Guofeng, Takiff Howard E, Gao Qian

Abstract excerpt

Compensatory mutations have been suggested to promote multidrug-resistant tuberculosis (MDR-TB) transmission, but their role in facilitating the recent transmission of MDR-TB is unclear. To investigate the epidemiological significance of compensatory mutations, we analyzed a four-year population-based collection of MDR-TB strains from Shanghai (the most populous city in China) and 1346 published global MDR-TB...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antitubercular Agents
Share to Bacterial Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA-Directed RNA Polymerases

Share to Drug Resistance, Bacterial

Share to Microbial Sensitivity Tests

Share to Mycobacterium tuberculosis

Share to Tuberculosis, Multidrug-Resistant

Source

Open in PubMed Open full text

Identifiers

PMID: 29872078
DOI: 10.1038/s41426-018-0101-6
PMCID: PMC5988693

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Have compensatory mutations facilitated the current epidemic of multidrug-resistant tuberculosis?PMID 29872078Read ↗

Limited contribution of compensatory mutations to MDR/RR-TB clustering in Hunan Province, China: a population-based whole-genome sequencing study.Semantic proximity Read ↗

Characteristics of compensatory mutations in rifampicin-resistant tuberculosis and their association with compensated transmission in Ningbo, China.Semantic proximity Read ↗

Novel and Reported Compensatory Mutations in <i>rpoABC</i> Associate Specifically with Predominant <i>Mycobacterium tuberculosis</i> Rifampicin Resistance Marker <i>rpoB</i> :S450LSemantic proximity Read ↗

[Comprehensive identification of compensatory mutations in rifampicin-resistant Mycobacterium tuberculosis strains].Semantic proximity Read ↗

A 10-Year Comparative Analysis Shows that Increasing Prevalence of Rifampin-Resistant Mycobacterium tuberculosis in China Is Associated with the Transmission of Strains Harboring Compensatory Mutations.Semantic proximity Read ↗

Compensatory Mutations of Rifampin Resistance Are Associated with Transmission of Multidrug-Resistant Mycobacterium tuberculosis Beijing Genotype Strains in China.Semantic proximity Read ↗

Whole-genome sequencing of rifampicin-resistant Mycobacterium tuberculosis strains identifies compensatory mutations in RNA polymerase genes.Semantic proximity Read ↗

Genetic factors associated with acquired phenotypic drug resistance and its compensatory evolution during tuberculosis treatment.Semantic proximity Read ↗

Patterns of compensatory mutations in rpoA/B/C genes of multidrug resistant M. tuberculosis in Uganda.Semantic proximity Read ↗

Compensatory effects of M. tuberculosis rpoB mutations outside the rifampicin resistance-determining region.Semantic proximity Read ↗

Characteristics of compensatory mutations in the rpoC gene and their association with compensated transmission of Mycobacterium tuberculosis.Semantic proximity Read ↗

Effect of compensatory evolution in the emergence and transmission of rifampicin-resistant Mycobacterium tuberculosis in Cape Town, South Africa: a genomic epidemiology studySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.