Article
A 10-Year Comparative Analysis Shows that Increasing Prevalence of Rifampin-Resistant Mycobacterium tuberculosis in China Is Associated with the Transmission of Strains Harboring Compensatory Mutations.
Antimicrobial agents and chemotherapy - 1 Apr 2018
Huo Fengmin, Luo Jingjing, Shi Jin, Zong Zhaojing, Jing Wei, Dong Wenzhu, Dong Lingling, Ma Yifeng, Liang Qian, Shang Yuanyuan, Huang Hairong, Pang Yu
Abstract excerpt
In this work, we conducted bacterial population profile studies to assess trends of rifampin (RIF) resistance of Mycobacterium tuberculosis isolates collected across China from 2005 to 2015. Totals of 273 and 269 randomly selected M. tuberculosis isolates from 2005 and 2015, respectively, were analyzed. The rates of RIF resistance (36.4%), isoniazid resistance (39.0%), and levofloxacin resistance (25.7%) in 2015...
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