Article
Characteristics of compensatory mutations in the rpoC gene and their association with compensated transmission of Mycobacterium tuberculosis.
Frontiers of medicine - 1 Feb 2020
Wang Shengfen, Zhou Yang, Zhao Bing, Ou Xichao, Xia Hui, Zheng Yang, Song Yuanyuan, Cheng Qian, Wang Xinyang, Zhao Yanlin
Abstract excerpt
The aim of this study was to characterize rpoC gene mutations in Mycobacterium tuberculosis (MTB) and investigate the factors associated with rpoC mutations and the relation between rpoC mutations and tuberculosis (TB) transmission. A total of 245 MTB clinical isolates from patients with TB in six provinces and two municipalities in China were characterized based on gene mutations through DNA sequencing of rpoC...
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