Article
COMP-prohibitin 2 interaction maintains mitochondrial homeostasis and controls smooth muscle cell identity.
Cell death & disease - 4 Jun 2018
Jia Yiting, Wang Meili, Mao Chenfeng, Yu Fang, Wang Yingbao, Xiao Rui, Jiang Changtao, Zheng Lemin, Xu Qingbo, Zheng Ming, Fu Yi, Hu Qinghua, Kong Wei
Abstract excerpt
Vascular smooth muscle cells (VSMCs) are highly phenotypically plastic, and loss of the contractile phenotype in VSMCs has been recognized at the early onset of the pathology of a variety of vascular diseases. However, the endogenous regulatory mechanism to maintain contractile phenotype in VSMCs remains elusive. Moreover, little has been known about the role of the mitochondrial bioenergetics in terms of VSMC...
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