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Article

Cartilage oligomeric matrix protein maintains the contractile phenotype of vascular smooth muscle cells by interacting with alpha(7)beta(1) integrin.

Circulation research - 19 Feb 2010

Wang Li, Zheng Jingang, Du Yaoyao, Huang Yaqian, Li Jing, Liu Bo, Liu Chuan-ju, Zhu Yi, Gao Yuansheng, Xu Qingbo, Kong Wei, Wang Xian

Abstract excerpt

RATIONAL: Vascular smooth muscle cells (VSMCs) switching from a contractile/differentiated to a synthetic/dedifferentiated phenotype has an essential role in atherosclerosis, postangioplastic restenosis and hypertension. However, how normal VSMCs maintain the differentiated state is less understood. OBJECTIVE: We aimed to indentify the effect of cartilage oligomeric matrix protein (COMP), a normal vascular...

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Identifiers

PMID: 20019333
DOI: 10.1161/CIRCRESAHA.109.202762

Genes

COMP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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