Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Linezolid Kills Acid-Phase and Nonreplicative-Persister-Phase Mycobacterium tuberculosis in a Hollow-Fiber Infection Model

1 Jun 2018

Abstract excerpt

ABSTRACT The therapy for treatment of Mycobacterium tuberculosis infections is long and arduous. It has been hypothesized that the therapy duration is driven primarily by populations of organisms in different metabolic states that replicate slowly or not at all (acid-phase and nonreplicative-persister [NRP]-phase organisms). Linezolid is an oxazolidinone antimicrobial with substantial activity against Log-phase...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacteriophages and microbial interactions
Share to Mycobacterium research and diagnosis
Share to Tuberculosis Research and Epidemiology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29866864
DOI: 10.1128/aac.00221-18

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Linezolid Kills Acid-Phase and Nonreplicative-Persister-Phase Mycobacterium tuberculosis in a Hollow-Fiber Infection ModelPMID 29866864Read ↗

Combination Therapy to Kill Mycobacterium tuberculosis in Its Nonreplicating Persister Phenotype.Semantic proximity Read ↗

Linezolid for Infants and Toddlers With Disseminated Tuberculosis: First StepsSemantic proximity Read ↗

Time-dependent pharmacodynamics of amikacin on Mycobacterium abscessus growth and resistance emergenceSemantic proximity Read ↗

Bacterial Replication Rate Modulation in Combination with Antimicrobial Therapy: Turning the Microbe against Itself.Semantic proximity Read ↗

Antibiotic dose-response curves can measure antibiotic activity against <i>Mycobacterium abscessus</i> and <i>Mycobacterium peregrinum</i>Semantic proximity Read ↗

ODELAM: Rapid sequence-independent detection of drug resistance in clinical isolates of Mycobacterium tuberculosisSemantic proximity Read ↗

Emergence of phenotypic and genotypic antimicrobial resistance in Mycobacterium tuberculosis.Semantic proximity Read ↗

Targeting Phenotypically Tolerant Mycobacterium tuberculosisSemantic proximity Read ↗

High-throughput Screening of Compounds against Autoluminescent Nonreplicating <i>Mycobacterium tuberculosis</i> under Diverse ConditionsSemantic proximity Read ↗

Efflux-pump-derived multiple drug resistance to ethambutol monotherapy in Mycobacterium tuberculosis and the pharmacokinetics and pharmacodynamics of ethambutol.Semantic proximity Read ↗

Development of an in vitro model for Non-Replicating Persistent Mycobacterium tuberculosis, and an investigation of the novel phenotypeSemantic proximity Read ↗

Elucidating population-wide mycobacterial replication dynamics at the single-cell levelSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.