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Targeting Phenotypically Tolerant Mycobacterium tuberculosis

24 Feb 2017

Abstract excerpt

While the immune system is credited with averting tuberculosis in billions of individuals exposed to Mycobacterium tuberculosis, the immune system is also culpable for tempering the ability of antibiotics to deliver swift and durable cure of disease. In individuals afflicted with tuberculosis, host immunity produces diverse microenvironmental niches that support suboptimal growth, or complete growth arrest, of M....

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PMID: 28233509
DOI: 10.1128/microbiolspec.tbtb2-0031-2016

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