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High-throughput Screening of Compounds against Autoluminescent Nonreplicating <i>Mycobacterium tuberculosis</i> under Diverse Conditions

2024-03-11

Abstract excerpt

<h4>ABSTRACT</h4> The screening of new anti-mycobacterial chemicals is primarily focused on inhibiting the active growing bacteria. However, a major challenge in tuberculosis control is the ability of Mycobacterium tuberculosis to enter a nonreplicating state for extended periods, rendering it resistant to many clinical drugs and complicating eradication efforts. Existing low-oxygen-recovery assays designed for...

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Literature Corpus work
0f18212d-6027-5db7-82e9-31ec12cfae46
DOI
10.1101/2024.03.10.584296
Open publication

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High-throughput Screening of Compounds against Autoluminescent Nonreplicating <i>Mycobacterium tuberculosis</i> under Diverse ConditionsDOI 10.1101/2024.03.10.584296
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