Article

Development of an in vitro model for Non-Replicating Persistent Mycobacterium tuberculosis, and an investigation of the novel phenotype

2021-01-01

Abstract excerpt

Tuberculosis is the primary cause of global death by a single infectious agent. This widespread infection is assisted by the existence of a large reservoir of disease in the form of Latent Tuberculosis which is thought to infect over ¼ of the world's population. Latent Tuberculosis is caused when an existing Mycobacterium tuberculosis infection is encapsulated within a granuloma and the bacilli adapt their physiol...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: da96a8fb-f3e2-5732-b1a5-0f4bc2081007
DOI: 10.48780/publications.aston.ac.uk.00043264

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Development of an in vitro model for Non-Replicating Persistent Mycobacterium tuberculosis, and an investigation of the novel phenotypeDOI 10.48780/publications.aston.ac.uk.00043264Read

Complex, dynamic, and diverse phenotypes of stress/antibiotics-induced and natural subpopulations of Mycobacteriumtuberculosis.Semantic proximity Read

A novel in vitro multiple-stress dormancy model for Mycobacterium tuberculosis generates a lipid-loaded, drug-tolerant, dormant pathogen.Semantic proximity Read

Insights into the molecular determinants involved in Mycobacterium tuberculosis persistence and their therapeutic implicationsSemantic proximity Read

Phenotypic adaptation of Mycobacterium tuberculosis to host-associated stressors that induce persister formationSemantic proximity Read

Targeting Phenotypically Tolerant Mycobacterium tuberculosisSemantic proximity Read

Candidate transmission survival genome of Mycobacterium tuberculosisSemantic proximity Read

Profiling the Proteome of Mycobacterium tuberculosis during Dormancy and ReactivationSemantic proximity Read

Exploring the Genetic Landscape of Mycobacterium tuberculosis: Unlocking the Differences in Between Latent and Active Tuberculosis.Semantic proximity Read

Potassium availability triggers Mycobacterium tuberculosis transition to, and resuscitation from, non-culturable (dormant) states.Semantic proximity Read

The Mycobacterium tuberculosis: A Silent KillerSemantic proximity Read

Transcriptional Profiling of Mycobacterium tuberculosis Exposed toIn VitroLysosomal StressSemantic proximity Read

Drug-Tolerant Mycobacterium tuberculosis Adopt Different Survival Strategies in Alveolar Macrophages of Patients with Pulmonary TuberculosisSemantic proximity Read