Article
10-Year Experience with HLA-G in Heart Transplantation.
Human immunology - 1 Aug 2018
Lazarte Julieta, Adamson Mitchell B, Tumiati Laura C, Delgado Diego H
Abstract excerpt
The Human Leukocyte Antigen-G (HLA-G) is a MHC-class Ib molecule with robust immunomodulatory properties; in transplant, it inhibits cytotoxic activity of immune cells and thus has a pivotal role in protecting the allograft from immune attack. The present review details a 10-year experience investigating the influence of HLA-G on heart transplantation, allograft rejection and cardiac allograft vasculopathy...
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