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Article

Human leukocyte antigen-G donor-recipient matching of the 14-base pair polymorphism protects against cancer after heart transplant.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation - 1 Jul 2020

Adamson Mitchell B, Ribeiro Roberto V P, Yu Frank, Lazarte Julieta, Runeckles Kyle, Manlhiot Cedric, Rao Vivek, Delgado Diego H

Abstract excerpt

BACKGROUND: After a transplant, cancer is a leading cause of morbidity and mortality. Human leukocyte antigen-G (HLA-G)-an immune checkpoint molecule-reduces allograft rejection by dampening host immune responses. Reports suggest malignant cells utilize HLA-G to evade the immune system and promote cancer development. Our objective was to evaluate HLA-G donor-recipient polymorphism matching and development of...

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Identifiers

PMID: 32317137
DOI: 10.1016/j.healun.2020.03.024

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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