Article
14-Base pair polymorphism of human leukocyte antigen-G as genetic determinant in heart transplantation and cyclosporine therapy monitoring.
Human immunology - 1 Oct 2009
Torres M I, Luque J, Lorite P, Isla-Tejera B, Palomeque T, Aumente M D, Arizon J, Peña J
Abstract excerpt
The 14-base pair (bp) polymorphism within the HLA-G gene has been investigated in heart transplant patients for the first time. The 14-bp polymorphism is associated with HLA-G mRNA stability and the patterns of alternative isoforms splicing, and therefore may influence the functionality of the HL...
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