Article
New Developments in HLA-G in Cardiac Transplantation.
Human immunology - 1 Sept 2016
Lazarte Julieta, Tumiati Laura C, Rao Vivek, Delgado Diego H
Abstract excerpt
Human Leukocyte Antigen-G (HLA-G) is a non-classical class 1b protein, whose gene is located on chromosome 6 (6p21.31). HLA-G inhibits the immune cells' cytotoxic activity by interacting with specific receptors on their membranes. Since it is a naturally occurring immune modulator, HLA-G has been investigated in transplantation. Indeed, a number of investigations reveal that HLA-G expression is influenced by...
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