Article
Can HLA-G polymorphisms predict the development of cardiac allograft vasculopathy?
Human immunology - 1 Apr 2013
Mociornita Amelia G, Lim-Shon Jongsung, Joseph Jemy M, Ross Heather J, Rao Vivek, Delgado Diego H
Abstract excerpt
A 14 bp insertion/deletion polymorphism in exon 8 of the HLA-G gene is associated with mRNA stability and HLA-G expression. In cardiac transplantation, the 14 bp deletion polymorphism plays an important role in the expression of HLA-G and is associated with fewer episodes of cellular rejection. We investigated the association between the 14 bp insertion/deletion HLA-G polymorphism and cardiac allograft...
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