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Biological Characteristics of HLA-G and Its Role in Solid Organ Transplantation

13 Jun 2022

Abstract excerpt

Organ transplantation is a lifesaving option for patients with advanced diseases. Rejection is regarded as one of the most severe risk factors post-transplantation. A molecule that contributes to immune tolerance and resisting rejection is human leukocyte antigen (HLA)-G, which belongs to the non-classical major histocompatibility complex class (MHC) I family. HLA-G was originally found to play a role during...

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PMID: 35769475
DOI: 10.3389/fimmu.2022.902093

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