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Article

In Silico Typing of Classical and Non-classical HLA Alleles from Standard RNA-Seq Reads.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2018

Boegel Sebastian, Bukur Thomas, Castle John C, Sahin Ugur

Abstract excerpt

Next-Generation Sequencing (NGS) enables the rapid generation of billions of short nucleic acid sequence fragments (i.e., "sequencing reads"). Especially, the adoption of gene expression profiling using whole transcriptome sequencing (i.e., "RNA-Seq") has been rapid. Here, we describe an in silico method, seq2HLA, that takes standard RNA-Seq reads as input and determines a sample's (classical and non-classical)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29858809
DOI: 10.1007/978-1-4939-8546-3_12

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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