Article
Fine-mapping analysis of the MHC region for vitiligo based on a new Han-MHC reference panel.
Gene - 30 Mar 2018
Yang Chao, Wu Juan, Zhang Xuelei, Wen Leilei, Sun Jingying, Cheng Yuyan, Tang Xianfa, Liang Bo, Chen Gang, Zhou Fusheng, Cui Yong, Zhang Anping, Zhang Xuejun, Zheng Xiaodong, Yang Sen, Sun Liangdan
Abstract excerpt
Vitiligo is an immune-related disease with patchy depigmentation of skin and hair caused by selective destruction of melanocytes. In recent decades, many studies have shown the association between vitiligo and HLA genes; however, the results of Han Chinese are scarce. In this study, we performed a fine-mapping analysis of the MHC region in 2818 Han Chinese subjects through a widely used HLA imputation method with...
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