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Article

The Genetics of Pemphigus Vulgaris

14 Aug 2018

Abstract excerpt

Pemphigus vulgaris (PV) is a severe autoimmune blistering disease caused by auto-antibodies (auto-Abs) directed against epithelial desmosomal components and leading to disruption of cell-cell adhesion. The exact mechanisms underlying the disease pathogenesis remain unknown and treatment is still based on immunosuppressive drugs, such as corticosteroids, which are associated with potentially significant side...

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PMID: 30155467
DOI: 10.3389/fmed.2018.00226

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