Fine Mapping Analysis of the MHC Region to Identify Variants Associated With Chinese Vitiligo and SLE and Association Across These Diseases.

doi:10.3389/fimmu.2021.758652

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Fine Mapping Analysis of the MHC Region to Identify Variants Associated With Chinese Vitiligo and SLE and Association Across These Diseases.

Frontiers in immunology - 1 Jan 2021

Cao Lu, Zhang Ruixue, Wang Yirui, Hu Xia, Yong Liang, Li Bao, Ge Huiyao, Chen Weiwei, Zhen Qi, Yu Yafen, Mao Yiwen, Li Zhuo, Fan Wencheng, Sun Liangdan

Abstract excerpt

The important role of MHC in the pathogenesis of vitiligo and SLE has been confirmed in various populations. To map the most significant MHC variants associated with the risk of vitiligo and SLE, we conducted fine mapping analysis using 1117 vitiligo cases, 1046 SLE cases and 1693 healthy control subjects in the Han-MHC reference panel and 1000 Genomes Project phase 3. rs113465897 (P=1.03×10-13, OR=1.64, 95%CI...

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PMID: 35082778
DOI: 10.3389/fimmu.2021.758652
PMCID: PMC8784546

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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