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Article

Patient‐shared TCRβ‐CDR3 clonotypes correlate with favorable prognosis in chronic hepatitis B

1 Jun 2018

Abstract excerpt

Abstract The presence of shared T‐cell clonotypes was found in several different diseases, but its relationship with the progression of disease remains unclear. By sequencing the complementary determining region 3 of T‐cell receptor (TCR) β chains from the purified antigen‐experienced CD8+ T cells, we characterized the T‐cell repertoire in a prospective cohort study among 75 patients with chronic hepatitis B in...

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PMID: 29856484
DOI: 10.1002/eji.201747327

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