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Article

Identification of Antigen-Specific B Cell Receptor Sequences Using Public Repertoire Analysis

1 Jan 2014

Abstract excerpt

High-throughput sequencing allows detailed study of the BCR repertoire postimmunization, but it remains unclear to what extent the de novo identification of Ag-specific sequences from the total BCR repertoire is possible. A conjugate vaccine containing Haemophilus influenzae type b (Hib) and group C meningococcal polysaccharides, as well as tetanus toxoid (TT), was used to investigate the BCR repertoire of adult...

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PMID: 25392534
DOI: 10.4049/jimmunol.1401405

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