Article
Host ethnicity and virus genotype shape the hepatitis B virus-specific T-cell repertoire.
Journal of virology - 1 Nov 2008
Tan Anthony Tanoto, Loggi Elisabetta, Boni Carolina, Chia Adeline, Gehring Adam J, Sastry Konduru S R, Goh Vera, Fisicaro Paola, Andreone Pietro, Brander Christian, Lim Seng Gee, Ferrari Carlo, Bihl Florian, Bertoletti Antonio
Abstract excerpt
Repertoire composition, quantity, and qualitative functional ability are the parameters that define virus-specific T-cell responses and are linked with their potential to control infection. We took advantage of the segregation of different hepatitis B virus (HBV) genotypes in geographically and genetically distinct host populations to directly analyze the impact that host and virus variables exert on these...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
