Article
T cell receptor repertoire profiling predicts the prognosis of HBV-associated hepatocellular carcinoma.
Cancer medicine - 1 Aug 2018
Lin Kai-Rong, Deng Fei-Wen, Jin Ya-Bin, Chen Xiang-Ping, Pan Ying-Ming, Cui Jin-Huan, You Zhi-Xuan, Chen Huan-Wei, Luo Wei
Abstract excerpt
Tumor-infiltrating T cell repertoire has been demonstrated to be closely associated with anti-tumor immune response. However, the relationship between T cell repertoire in tumor tissue and prognosis has never been reported in Hepatocellular carcinoma (HCC). We performed the high-throughput T cell receptor (TCR) sequencing to systematically characterize the infiltrating T cell repertoires of tumor and matched...
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