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Article

Taq1A polymorphism and medication effects on inhibitory action control in Parkinson disease.

Brain and behavior - 1 Jul 2018

McDonell Katherine E, van Wouwe Nelleke C, Harrison Madaline B, Wylie Scott A, Claassen Daniel O

Abstract excerpt

BACKGROUND: Dopamine therapy in Parkinson disease (PD) can have differential effects on inhibitory action control, or the ability to inhibit reflexive or impulsive actions. Dopamine agonist (DAAg) medications, which preferentially target D2 and D3 receptors, can either improve or worsen control of impulsive actions in patients with PD. We have reported that the direction of this effect depends on baseline levels...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29856137
DOI: 10.1002/brb3.1008
PMCID: PMC6043698

Genes

DRD2
DRD3

Provenance

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