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Article

Analysis of DRD4 and DAT polymorphisms and behavioral inhibition in healthy adults: implications for impulsivity.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Jan 2008

Congdon Eliza, Lesch Klaus Peter, Canli Turhan

Abstract excerpt

Impulsivity, a highly prevalent symptom in multiple psychiatric disorders, is a partially heritable trait influenced by specific biological mechanisms. In particular, dopamine is proposed to play a role in impulsive behaviors and recent studies have implicated functional polymorphisms of dopamine-related genes in impulsive behaviors across different clinical and behavioral classifications. However, most have not...

Topics

Adolescent
Adult
Alleles
Dopamine Plasma Membrane Transport Proteins
Female
Genetic Variation
Genotype
Humans
Impulsive Behavior
Inhibition, Psychological

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Polymorphism, Genetic

Receptors, Dopamine D4

Source

Identifiers

PMID: 17525955
DOI: 10.1002/ajmg.b.30557

Genes

DRD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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