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Article

Opposite effects of DRD2 gene polymorphisms on inhibitory control and motor output in antisaccade task in healthy subjects and schizophrenia patients.

Molecular biology reports - 8 Jan 2026

Kirenskaya Anna V, Novototsky-Vlasov Vladimir Y, Kibitov Alexander O, Merkulova Tamara V, Tkachenko Andrej A, Storozheva Zinaida I

Abstract excerpt

BACKGROUND: Dopamine is one of the neurotransmitters that have been implicated in schizophrenia. Researchers suggest that certain D2 receptors (DRD2) gene polymorphisms alter dopaminergic signaling and influence prefrontally-mediated executive functions. The present study aims to test the effects of DRD2 rs6277, rs6275 and rs2242592 polymorphisms on cognitive and motor measures of antisaccade task (AS) in healthy...

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Identifiers

PMID: 41505003
DOI: 10.1007/s11033-025-11419-w

Genes

DRD2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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