Article
Dopaminergic influences on executive function and impulsive behaviour in impulse control disorders in Parkinson's disease.
Journal of neuropsychology - 1 Sept 2013
Leroi Iracema, Barraclough Michelle, McKie Shane, Hinvest Neal, Evans Jonathan, Elliott Rebecca, McDonald Kathryn
Abstract excerpt
The development of impulse control disorders (ICDs) in Parkinson's disease (PD) may arise from an interaction among cognitive impairment, impulsive responding and dopaminergic state. Dopaminergic state may be influenced by pharmacologic or genotypic (catechol-O-methyltransferase; COMT) factors. We sought to investigate this interaction further by comparing those with (n = 35) and without (n = 55) ICDs on...
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