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Article

Genetic variation in the dopamine system is associated with mixed-strategy decision-making in patients with Parkinson's disease.

The European journal of neuroscience - 1 Dec 2023

Parr Ashley C, Riek Heidi C, Coe Brian C, Pari Giovanna, Masellis Mario, Marras Connie, Munoz Douglas P

Abstract excerpt

Decision-making during mixed-strategy games requires flexibly adapting choice strategies in response to others' actions and dynamically tracking outcomes. Such decisions involve diverse cognitive processes, including reinforcement learning, which are affected by disruptions to the striatal dopamine system. We therefore investigated how genetic variation in dopamine function affected mixed-strategy decision-making...

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PMID: 36453013
DOI: 10.1111/ejn.15875

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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