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Article

Dopamine Gene Profiling to Predict Impulse Control and Effects of Dopamine Agonist Ropinirole.

Journal of cognitive neuroscience - 1 Jul 2016

MacDonald Hayley J, Stinear Cathy M, Ren April, Coxon James P, Kao Justin, Macdonald Lorraine, Snow Barry, Cramer Steven C, Byblow Winston D

Abstract excerpt

Dopamine agonists can impair inhibitory control and cause impulse control disorders for those with Parkinson disease (PD), although mechanistically this is not well understood. In this study, we hypothesized that the extent of such drug effects on impulse control is related to specific dopamine gene polymorphisms. This double-blind, placebo-controlled study aimed to examine the effect of single doses of 0.5 and...

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Identifiers

PMID: 26942320
DOI: 10.1162/jocn_a_00946

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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