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Article

Dopamine effects on memory load and distraction during visuospatial working memory in cognitively normal Parkinson's disease.

Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition - 1 Nov 2021

Bayram Ece, Litvan Irene, Wright Brenton A, Grembowski Cailey, Shen Qian, Harrington Deborah L

Abstract excerpt

Visuospatial working memory (WM) impairments in Parkinson's disease (PD) are more prominent and evolve earlier than verbal WM deficits, suggesting some differences in underlying pathology. WM is regulated by dopaminergic neurotransmission in the prefrontal cortex, but the effect of dopamine on specific processes supporting visuospatial WM are not well understood. Dopamine therapeutic effects on different WM...

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Identifiers

PMID: 33021874
DOI: 10.1080/13825585.2020.1828804
PMCID: PMC8021591

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