Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Motor impulsivity in Parkinson disease: associations with COMT and DRD2 polymorphisms.

Scandinavian journal of psychology - 1 Jun 2014

Ziegler David A, Ashourian Paymon, Wonderlick Julien S, Sarokhan Alison K, Prelec Drazen, Scherzer Clemens R, Corkin Suzanne

Abstract excerpt

Parkinson disease (PD) is an age-related degenerative disease of the brain, characterized by motor, cognitive, and psychiatric symptoms. Neurologists and neuroscientists now understand that several symptoms of the disease, including hallucinations and impulse control behaviors, stem from the dopaminergic medications used to control the motor aspects of PD. Converging evidence from animals and humans suggests that...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Alleles

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Catechol O-Methyltransferase

Share to Impulsive Behavior

Share to Inhibition, Psychological

Share to Parkinson Disease

Share to Polymorphism, Genetic

Share to Receptors, Dopamine D2

Source

Open in PubMed Open full text

Identifiers

PMID: 24749760
DOI: 10.1111/sjop.12113
PMCID: PMC5751699

Genes

COMT
DRD2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Motor impulsivity in Parkinson disease: associations with COMT and DRD2 polymorphisms.PMID 24749760Read ↗

Genetic markers of striatal dopamine predict individual differences in dysfunctional, but not functional impulsivity.Semantic proximity Read ↗

Analysis of DRD4 and DAT polymorphisms and behavioral inhibition in healthy adults: implications for impulsivity.Semantic proximity Read ↗

Taq1A polymorphism and medication effects on inhibitory action control in Parkinson disease.Semantic proximity Read ↗

Dopaminergic influences on executive function and impulsive behaviour in impulse control disorders in Parkinson's disease.Semantic proximity Read ↗

Role of genetic polymorphisms of the dopaminergic system in Parkinson's disease patients with impulse control disorders.Semantic proximity Read ↗

More than an “inverted-U”? An exploratory study of the association between the catechol-o-methyltransferase gene polymorphism and executive functions in Parkinson’s diseaseSemantic proximity Read ↗

Genetic variations in dopamine and inhibitory control: lack of influence on action restraint.Semantic proximity Read ↗

Evaluation of genetic variability in the dopamine receptor D2 in relation to behavioral inhibition and impulsivity/sensation seeking: an exploratory study with d-amphetamine in healthy participants.Semantic proximity Read ↗

Association between the Catechol O-methyltransferase (COMT) Val158met polymorphism and different dimensions of impulsivity.Semantic proximity Read ↗

Association of the COMT Met¹⁵⁸ allele with trait impulsivity in healthy young adults.Semantic proximity Read ↗

COMT val158met moderation of dopaminergic drug effects on cognitive function: a critical review.Semantic proximity Read ↗

Interactions of COMT and ALDH2 Genetic Polymorphisms on Symptoms of Parkinson’s DiseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.