Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

DNA Modifications: Naturally More Error Prone?

Trends in genetics : TIG - 1 Aug 2018

Tomkova Marketa, Schuster-Böckler Benjamin

Abstract excerpt

Epigenetic DNA modifications are essential for normal cell function in vertebrates, but they can also be hotspots of mutagenesis. Methylcytosine in particular has long been known to be less stable than other nucleotides and spontaneously deaminates to thymine. Beyond this well-established phenomenon, however, the influence of epigenetic marks on mutagenesis has recently become an active field of investigation. In...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CpG Islands
Share to DNA Repair
Share to DNA Replication

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Epigenesis, Genetic

Share to Mutagenesis

Share to Smoking

Share to Sunlight

Share to Ultraviolet Rays

Source

Identifiers

PMID: 29853204
DOI: 10.1016/j.tig.2018.04.005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

DNA Modifications: Naturally More Error Prone?PMID 29853204Read ↗

DNA methylation and mutation.Semantic proximity Read ↗

Endogenously generated DNA nucleobase modifications source, and significance as possible biomarkers of malignant transformation risk, and role in anticancer therapy.Semantic proximity Read ↗

Investigating the origins of the mutational signatures in cancer.Semantic proximity Read ↗

DNA Damage, Mutagenesis and CancerSemantic proximity Read ↗

From DNA damage to mutations: All roads lead to aging.Semantic proximity Read ↗

Generation of mutator mutants during carcinogenesis.Semantic proximity Read ↗

Unboxing the molecular modalities of mutagens in cancerSemantic proximity Read ↗

32nd annual meeting of European Environmental Mutagen Society. DNA damage and repair fundamental aspects and contribution to human disorders.Semantic proximity Read ↗

Cytotoxicity and mutagenicity of endogenous DNA base lesions as potential cause of human aging.Semantic proximity Read ↗

Establishing Linkages Among DNA Damage, Mutagenesis, and Genetic Diseases.Semantic proximity Read ↗

Epigenetics, DNA damage, and aging.Semantic proximity Read ↗

Assessment of genetic damage in healthy and diseased tissue.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.