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DNA Damage, Mutagenesis and Cancer

23 Mar 2018

Abstract excerpt

A large number of chemicals and several physical agents, such as UV light and γ-radiation, have been associated with the etiology of human cancer. Generation of DNA damage (also known as DNA adducts or lesions) induced by these agents is an important first step in the process of carcinogenesis. Evolutionary processes gave rise to DNA repair tools that are efficient in repairing damaged DNA; yet replication of...

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PMID: 29570697
DOI: 10.3390/ijms19040970

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