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Assessment of genetic damage in healthy and diseased tissue.

IARC scientific publications - 1 Jan 2011

Shuga Joe, Hainaut Pierre, Smith Martyn T

Abstract excerpt

DNA, along with other cellular components, is under constant attack by chemical, physical, and infectious agents present in the human environment, as well as by reactive metabolites generated by physiological processes. Mutations occur as the consequence of this damage, but may also be caused by improper DNA repair of alterations occurring during normal DNA replication and transcription. Genetic damage can occur...

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PMID: 22997857

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