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Article

Interplay between the APOE Genotype and Possible Plasma Biomarkers in Alzheimer's Disease.

Current Alzheimer research - 1 Jan 2018

Zverova Martina, Kitzlerova Eva, Fisar Zdenek, Jirak Roman, Hroudova Jana, Benakova Hana, Lelkova Petra, Martasek Pavel, Raboch Jiri

Abstract excerpt

BACKGROUND: Alzheimer's disease (AD) is a progressive neurodegenerative disorder with a complex pathogenesis and a common occurrence of comorbid diseases such as depression. It is accepted that the presence of the ε4 allele of the gene that encodes apolipoprotein E (APOE) is the strongest genetic risk factor for the development of sporadic AD. Melatonin, cortisol, homocysteine, and prolactin are presumed to be...

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Identifiers

PMID: 29852871
DOI: 10.2174/1567205015666180601090533

Genes

APOE

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