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Article

HPA axis dysregulation associated to apolipoprotein E4 genotype in Alzheimer's disease.

Journal of Alzheimer's disease : JAD - 1 Jan 2010

Gil-Bea Francisco J, Aisa Barbara, Solomon Alina, Solas Maite, del Carmen Mugueta Maria, Winblad Bengt, Kivipelto Miia, Cedazo-Mínguez Angel, Ramírez María J

Abstract excerpt

The present work investigated the involvement of cortisol and its receptors, glucocorticoid receptor (GR) and mineralocorticoid receptor (MR), in Alzheimer's disease (AD). Cortisol was measured in cerebrospinal fluid (CSF) samples from controls, mild cognitive impairment (MCI), progressive MCI evolving to AD, and AD. CSF cortisol levels do not seem to have a prognostic value, as increases in cortisol levels were...

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Identifiers

PMID: 20858975
DOI: 10.3233/JAD-2010-100663

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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