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The relationship between cortisol and cognitive function in healthy older people: The moderating role of Apolipoprotein E polymorphism.

Neurobiology of learning and memory - 1 Nov 2018

Montoliu Teresa, Hidalgo Vanesa, Pulopulos Matias M, Ivorra José Luis, Martínez María José, Salvador Alicia

Abstract excerpt

The Apolipoprotein E4 (ApoE-ε4) allele has been suggested as the main risk factor for late onset Alzheimer's disease (AD), whereas the ApoE-ε2 allele has been proposed as a protective factor. These proposals have increased the interest in the effect of the ApoE genotype in healthy people. Additionally, high cortisol levels have been related to negative effects on cognition. However, few studies have investigated...

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Identifiers

PMID: 30130588
DOI: 10.1016/j.nlm.2018.08.013

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