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Article

Analysis of Helios gene expression and Foxp3 TSDR methylation in the newly diagnosed Rheumatoid Arthritis patients

31 May 2018

Abstract excerpt

BACKGROUND: The control of auto-reactive cells is defective in rheumatoid arthritis (RA). Regulatory T (Treg) cells which play a key role in the modulation of immune responses have an impaired function in RA. Foxp3 is a master regulator of Treg cells which its expression is under the tight control of epigenetic mechanisms. In the current study, we analyzed the epigenetic modulation of the Foxp3 Treg-specific...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 29851536
DOI: 10.1080/08820139.2018.1480029

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