Article
Tespa1 is associated with susceptibility but not severity of rheumatoid arthritis in the Zhejiang Han population in China.
Clinical rheumatology - 1 Apr 2015
Yao Yunliang, Zhang Hui, Shao Shengwen, Cui Ge, Zhang Ting, Sun Hui
Abstract excerpt
Observational and experimental studies in animal models have shown that Tespa1 may be associated with B cell function and the onset of rheumatoid arthritis (RA). We hypothesized that Tespa1 may also play an important role in patients with RA. To test this hypothesis, we investigated the expression level, gene polymorphisms, and promoter methylation of the Tespa1 gene in 77 RA patients and 113 matched healthy...
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