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Article

Contribution of Dysregulated DNA Methylation to Autoimmunity.

International journal of molecular sciences - 2 Nov 2021

Funes Samanta C, Fernández-Fierro Ayleen, Rebolledo-Zelada Diego, Mackern-Oberti Juan P, Kalergis Alexis M

Abstract excerpt

Epigenetic mechanisms, such as DNA methylation, histone modifications, and non-coding RNAs are known regulators of gene expression and genomic stability in cell growth, development, and differentiation. Because epigenetic mechanisms can regulate several immune system elements, epigenetic alterations have been found in several autoimmune diseases. The purpose of this review is to discuss the epigenetic...

Topics

Animals
Autoimmune Diseases
DNA Methylation
Epigenesis, Genetic
Genetic Predisposition to Disease
Histone Code
Humans

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 34769338
DOI: 10.3390/ijms222111892
PMCID: PMC8584328

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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