Article
Prevalence and patterns of rifampicin and isoniazid resistance conferring mutations in Mycobacterium tuberculosis isolates from Uganda.
PloS one - 1 Jan 2018
Kigozi Edgar, Kasule George W, Musisi Kenneth, Lukoye Deus, Kyobe Samuel, Katabazi Fred Ashaba, Wampande Eddie M, Joloba Moses L, Kateete David Patrick
Abstract excerpt
BACKGROUND: Accurate diagnosis of tuberculosis, especially by using rapid molecular assays, can reduce transmission of drug resistant tuberculosis in communities. However, the frequency of resistance conferring mutations varies with geographic location of Mycobacterium tuberculosis, and this affects the efficiency of rapid molecular assays in detecting resistance. This has created need for characterizing drug...
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