Article
Isoniazid and rifampicin resistance-associated mutations in Mycobacterium tuberculosis isolates from Yangon, Myanmar: implications for rapid molecular testing.
The Journal of antimicrobial chemotherapy - 1 Oct 2009
Valvatne Håvard, Syre Heidi, Kross Martijn, Stavrum Ruth, Ti Ti, Phyu Sabai, Grewal Harleen M S
Abstract excerpt
OBJECTIVES: To evaluate the frequency and nature of mutations in genes associated with resistance to rifampicin and isoniazid in Mycobacterium tuberculosis isolates collected from Yangon, Myanmar. METHODS: Ninety-six isoniazid-resistant M. tuberculosis isolates, including 29 multidrug-resistant isolates, were analysed for mutations in the rpoB, katG, inhA, oxyR and ahpC genes. RESULTS: Mutations in the rpoB gene...
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