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TNFSF4 is a risk factor to systemic lupus erythematosus in a Latin American population.

Clinical rheumatology - 1 Mar 2021

Moreno-Eutimio Mario Adán, Martínez-Alemán Carmen Estefanía, Aranda-Uribe Ivan Sammir, Aquino-Jarquin Guillermo, Cabello-Gutierrez Carlos, Fragoso José Manuel, Barbosa-Cobos Rosa Elda, Saavedra Miguel A, Ramírez-Bello Julian

Abstract excerpt

OBJECTIVE: The aim of this study was to examine the association of three TNFSF4 single nucleotide variants (SNVs) with systemic lupus erythematosus (SLE) susceptibility in Mexican patients. METHODS: Genotypes of the TNFSF4 rs1234315T/C, rs2205960G/T, and rs704840T/G SNVs were determined using a TaqMan assay. In our study, we included 395 patients with SLE and 500 controls. RESULTS: Our information shows a...

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PMID: 32809147
DOI: 10.1007/s10067-020-05332-9

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