Article
Intronic variant of EGFR is associated with GBAS expression and survival outcome of early-stage non-small cell lung cancer.
Thoracic cancer - 1 Aug 2018
Hong Mi Jeong, Lee Shin Yup, Choi Jin Eun, Kang Hyo-Gyoung, Do Sook Kyung, Lee Jang Hyuck, Yoo Seung Soo, Lee Eung Bae, Seok Yangki, Cho Sukki, Jheon Sanghoon, Lee Jaehee, Cha Seung Ick, Kim Chang Ho, Park Jae Yong
Abstract excerpt
BACKGROUND: Genome-wide association studies have indicated that most of the currently identified disease and trait-associated single nucleotide polymorphisms (SNPs) are intronic or intergenic. RegulomeDB is a recently developed database that provides functional annotations for regulatory features of SNPs located in non-coding regions. We evaluated the potential regulatory SNPs in the EGFR gene region using...
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